Eicosapentaenoic Acid in Diabetes

The ratio of serum eicosapentaenoic acid to arachidonic acid is associated with renal impairment and diabetic macroangiopathies in elderly patients with type 2 diabetes.

A low ratio of serum eicosapentaenoic acid to arachidonic acid (EPA/AA) has been reported to correlate with coronary heart disease (1–3), and no previous studies have investigated serum polyunsaturated fatty acid (PUFA) levels exclusively in patients with diabetes, in whom atherosclerotic diseases are commonly found. We therefore examined the association between serum EPA/AA ratio and the preva...

P-200: Effects of The ?3 Fatty Acid Eicosapentaenoic Acid on PPARa and Aromatase in Human Granulosa Cells

Effect of EPA and vitamin C on superoxide dismutase, glutathione peroxidase, total antioxidant capacity and malondialdehyde in type 2 diabetic patients.

OBJECTIVES The aim of this study is to investigate the effect of eicosapentaenoic acid combined with vitamin C in comparison with the pure form of eicosapentaenoic acid on the serum concentration of malondialdehyde, erythrocyte activity of superoxide dismutase, glutathione peroxidase, and the serum level of total antioxidant capacity in patients with type 2 diabetes. METHODS Eighty one male d...

Seasonal variations of ω3 polyunsaturated fatty acids in muscle of Capoeta caelestis

In this study, seasonal variations of fatty acid amounts in muscle tissues of Capoeta caelestis were investigated. We have found that the ω3 contents of C. caelestis in spring, summer, autumn and winter were 17.43%, 15.29%, 17.54%, 13.63% in female and 16.96%, 19.25%, 18.66%, 14.76% in male, respectively. The amounts of ω3 polyunsaturated fatty acids were higher than those of ω6 polyunsaturated...

Correlation between lipid-lowering and bone-protective effects of eicosapentaenoic acid in rats with steroid-induced bone loss

This study was conducted to investigate the correlation between lipid-lowering and bone-protective effects of eicosapentaenoic acid on steroid-induced bonechanges in rats. Twenty-one male 10-week-old Wistar rats were divided into 3 groups (n = 7 each) and treated with 0.9% NaCl SC (group 1) or methylprednisolone 7 mg/kg SC once a week (group 2) or methylprednisolone 7 mg/kg SC once a week + eic...

Comparison of the Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on the Eradication of Helicobacter pylori Infection, Serum Inflammatory Factors and Total Antioxidant Capacity

Helicobacter pylori infection, the most common chronic bacterial infection in the world, and an important cause of gastrointestinal disorders, may be involved in the pathogenesis of some extra-gastrointestinal disturbances, as well as an increase in blood levels of certain inflammatory markers. Anti-bacterial activity against Helicobacter pylori and anti-inflammatory properties of omega-3 fatty...